Could Topher Grace Carry an Entire Venom Movie?

To be honest, I actually think a Spider-Man spinoff focusing solely on Venom would be a good way to rejuvenate the Spider-Man franchise, since Spidey's stories themselves seem to be getting pretty tiresome. It seems like this idea is going to work out well for the X-Men series, as they devote one whole movie to Wolverine's story.
However, while it sounds like the bigwigs at Sony are interested in the Venom movie idea, they're not convinced that Topher Grace — who played Venom in the last Spidey flick — could carry an entire blockbuster superhero movie.
What do you think? Would you want to watch Topher venomize for a full movie? And if not Topher, then who?
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